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Destiny 2's Witch Queen expansion introduced Savathun's Throne World, a new activity space that features The Wellspring and three new Lost Sectors. Sepulcher is one such Lost Sector and is arguably the easiest of the bunch. So long as you have a good loadout, you should be able to farm Sepulcher without much issue.

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Master Sepulcher features over half a dozen Champions, minimal shields, and small combat spaces that pair nicely with Solar 3.0 and even Warmind Cells. This guide will cover all the modifiers tied to Master Sepulcher and the best strategies for safe and quick Lost Sector clears.

Updated January 15, 2023, by Charles Burgar: Season of the Seraph has refreshed all Artifact mods, allowing GLs to stun Unstoppable Champions among a Primary anti-Champion refresh. We've updated this guide with new loadout recommendations, referencing this season's new Champion counters and Exotic buffs that released in recent months.

Destiny 2 The Lament Exotic Sword

Sepulcher is one of the easier Throne World Lost Sectors. You won't find many shields, Champions spawn in pairs, and the Lightbearers in this Lost Sector can be easily avoided with good cover. Here's what you'll be dealing with.

Sepulcher Modifiers

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Sepulcher: Entrance

Destiny 2 Sepulcher Lost Sector First Room

Entrance Enemies

  • Two Barrier Knights
  • One Lightbearer Wizard
  • Knight (Arc)
  • Acolytes

You'll spawn atop of a Hive Knight kneeling beside a few Acolytes. Use your Heavy or a grenade to quickly break the Knight's shield. Clear the adds and continue. You'll enter a cube-shaped room with two overlooks at the back-end corners of the room. Each acts as a spawn point, first spawning a Barrier Knight. Both Knights spawn at once.

Now is a great time to proc an Ignite, chuck a grenade, or use any form of AoE damage to deal with the enemies. Stick to the back of the room, taking cover in the hallway you just came from. The Barrier Champions should be taken care of as soon as possible. Lower their health by around 20% to force their barrier to spawn. Break it to give yourself a small damage window. Repeat for the second Knight.

Defeating both Knights will spawn more adds and a Lightbearing Wizard. The Wizard is quite passive and will stick to the exit. You can wait to deal with the Wizard last if the adds are giving you problems. For the Wizard itself, stay at a distance while you lower its HP, equipping your Heavy weapon if it deploys a Rift. Be sure to crush its Ghost before you leave.

Sepulcher: Second Encounter

Destiny 2 Sepulcher Lost Sector Second Room

Second Encounter Enemies

  • Two Unstoppable Ogres
  • One Barrier Knight
  • One Lightbearer Acolyte
  • Acolytes
  • Thrall

You'll enter a short hallway before reaching the second room. A Barrier Knight will be guarding the hallway, so have your anti-Barrier counter at the ready.

This next room is similar to the last one. Swarms of Acolytes and Thrall will attempt to push you. Sunspots, Ignites, well-placed grenades, and Stasis can all shutdown these Hive in their tracks. Supporting the Hive will be two Unstoppable Ogres, one spawning immediately. Deal with the Ogre right as you enter the room or wait.

Killing enough Hive will cause a Lightbearing Acolyte to spawn. This Lightbearer is the deadliest, using a twisted version of the Blade Barrage Super to deal immense damage. Focus on the Lightbearer first, freezing or suppressing the target if you can. Stick to cover from the hallway to prevent getting hit by a blade. Once it's down, stun the Ogre and break the Ghost. Retreat to the hallway to finish clearing the room.

At this point, a second Unstoppable Ogre should spawn. Much like the first Ogre, stun and kill the Champion with your weapon of choice. Stunned Ogres take an immense amount of damage from your Heavy and Super. Clean up the remaining enemies, then make your way to the boss arena.

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Sepulcher: Boss

Destiny 2 Sepulcher Lost Sector Boss Room

Boss Fight Enemies

  • Knight Boss
  • Two Barrier Knights [Spawn delayed slightly]
  • Acolytes
  • Thralls

The final room in the Sepulcher Lost Sector plays just like the last two. You'll find a large group of Thrall kneeling in front of the Lost Sector chest. Killing the Thrall will spawn the boss, a massive Knight that is fairly easy to avoid. Stick to the back of the hallway you just came from, picking off the adds one by one.

Two Barrier Knights will spawn shortly after the boss spawns, one on each side of the room. They'll both move up to fight you. Focus on killing one Barrier at a time, alternating Barrier stuns as you damage them. This is a good time to use the rest of your Heavy or a charged Super. Defeat the Barrier Knights, quickly melt the boss, then open the chest to finish the Lost Sector.

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